I’d have said Email: A MacSparky Field Guide by David Sparks was the last word on email but I’d have been wrong. Maybe there can never be such a thing but an already very good go has just been improved. An updated version of the iBook is now available on the iBooks Store. Take a look at David Sparks’ official page about it for more details.
But while you’re at it, have a listen to him and colleague Katie Floyd on the latest MacPowerUsers podcast because that’s about the same thing. I’ve already read the original version of his book, my iPad is downloading the update as weak speak, but still I learnt some things from that.